Reacciones adversas a fármacos

Introduction: Adverse Drugs Reactions (ADR) can seriously affect health and are a frequent medical consultation cause. Sometimes can even go unnoticed if you do not take account of them. To evaluate knowledge and value that the medical team gives to the issue is fundamental in avoid morbidity...

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Publicado en:Revista Médica Universitaria
Autores principales: Anci, Cynthia, Carena, José, García Castellanos, Nicolás, Morea, Gastón, Salomón, Susana, Valli Caparroz, Diego
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Acceso en línea:https://bdigital.uncu.edu.ar/fichas.php?idobjeto=11039
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Artículo original
HospLagClinMed
HospLagClinMed
HospLagClinMed
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UNCuyo FCM
UNCuyo FCM
autor_str_mv Anci, Cynthia
Carena, José
García Castellanos, Nicolás
Morea, Gastón
Salomón, Susana
Valli Caparroz, Diego
disciplina_str_mv Ciencias médicas
descriptores_str_mv Conocimiento de la medicación por el médico
Efectos colaterales y reacciones adversas relacionados con medicamentos
Farmacovigilancia
description_str_mv Introduction: Adverse Drugs Reactions (ADR) can seriously affect health and are a frequent medical consultation cause. Sometimes can even go unnoticed if you do not take account of them. To evaluate knowledge and value that the medical team gives to the issue is fundamental in avoid morbidity and mortality of the ADR. Objectives: To determine the level of knowledge of ADR in the medical team. Reflect on the practice about the ADR. Material and methods: Descriptive cross-sectional study through a selfadministered, anonymous and validated survey with closed true / false answer questions on ADR of amiodarone, acenocoumarol, enalapril, furosemide, salbutamol, clonazepam and acetylsalicylic acid. The survey had 51 options for the drugs mentioned. It was consulted about pharmacological training, reading and thinking in ADR prior to prescription, as well as, experiences on the subject. Staff doctors (SD), resident doctors (RD) and 6th year medicine students (S) were included. Statistical analysis: measures of central tendency, scatter measures and Fisher\'s exact test. It was considered significant p <0.05. Outcomes: 107 people were surveyed; 85% were medical doctors (60.4% RD, 39.6% SD) and 15% S. 58.9% were women; average age: 31.3 years. 96% studied pharmacology as a curricular activity during their training. In the previous 6 months, 81.3% had read pharmacology and 16% had done some course about it. At prescribing, 54% thought ALWAYS about ADR, 6.54% report that NEVER read ADR before prescribing and 27.1% made it ALWAYS. 32% answered that they have NEVER had patients with serious ADR; 43% 1 to 3 TIMES and 25% MORE THAN 3 TIMES. About ADR in frequently used drugs, SD and RD answered correctly in 74% each one. Students answered correctly at 64%. About drugs, surveyed people responded correctly at enalapril n 60 (56.07%), acetylsalicylic acid n 57 (53.21%), prednisone n 54 (50.46), amiodarone n 21 (19.62%), salbutamol n 13 (12.14%), piperacillin tazobactam n 12 (11.21%), clonazepam n 12 (11.21%), furosemide n 3 (2.8%), and acenocoumarol n 1 (0.93%). From the comparative analysis between SD and RD, the ALWAYS response in ADR was more frequent in the first ones with SL (p = 0.08). We did not find differences in training or reading on ADR before prescribing between both groups. Conclusion: 54% ALWAYS thought about ADR at prescribing and only 27 referred to read ALWAYS this topic before an indication. The drug that showed less knowledge about was acenocoumarol and the one that showed best knowledge about was enalapril. The level of pharmacological instruction, even in elementary drugs, in public or private medical care system, is low. That is why is more pharmacovigilance is to be implemented in order to prevent ADR, as well as to make the health team aware of the importance of this problem.
Las reacciones adversas a fármacos (RAF) pueden afectar gravemente la salud y son motivo de consulta frecuente. Incluso pueden pasar desapercibidas si no se las piensa. Evaluar el conocimiento y valor que el equipo de salud otorga al tema, es fundamental para evitar la morbimortalidad de las RAF. Objetivos: Determinar el nivel de conocimiento de las reacciones adversas a fármacos (RAF) en el equipo de salud. Reflexionar sobre la propia práctica en relación a las RAF. Materiales y Métodos: Estudio descriptivo transversal a través de encuesta autoadministrada, anónima y validada, con preguntas cerradas de respuesta verdadero/falso sobre RAF de amiodarona, acenocumarol, enalapril, furosemida, salbutamol, clonazepam y ácido acetil salicílico. La encuesta constó de 51 opciones para las drogas citadas. Se consultó sobre la formación académica en farmacología, lectura y pensamiento en RAF previo a la prescripción así como experiencias sobre el tema. Se incluyeron médicos de planta (MP) médicos residentes (MR) y estudiantes (E) del 6º año de medicina. Análisis estadístico: medidas de tendencia central, medidas de dispersión y test exacto de Fisher. Se consideró significativa p<0.05. Resultados: Se encuestaron a 107 personas; 85% eran médicos (60.4% MR, 39.6% MP) y 15% E. El 58.9% fueron mujeres; edad promedio: 31.3 años. Cursaron farmacología como actividad curricular durante su formación el 96%. En los 6 meses previos, 81.3% refieren lecturas sobre farmacología y 16% realizó algún curso sobre el tema. Al momento de prescribir, 54% refieren que SIEMPRE pensaron en RAF. El 6.54% refiere que NUNCA lee previamente RAF antes de prescribir fármacos y 27.1% lo hacen SIEMPRE. El 32% contestó que NUNCA ha tenido pacientes con RAF graves; 43%, de 1 a 3 VECES y 25% MÁS DE 3 VECES. En relación a RAF habituales en drogas de uso frecuente los MP y MR respondieron correctamente el 74% cada uno. Conclusiones: El 54% refieren que SIEMPRE pensó en RAF al momento de prescribir y sólo el 27% refirió leer SIEMPRE sobre el tema antes de una indicación. El fármaco en que se demostró menos conocimiento fue acenocumarol y el mejor conocido fue el enalapril. El nivel de instrucción farmacológico, aún en drogas elementales en la salud pública/privada, es relativamente bajo por lo que se debiera implementar mayor fármacovigilancia para prevenir las RAF, como así también concientizar al equipo de salud sobre la importancia de esta problemática.
titulo_str_mv Reacciones adversas a fármacos
object_type_str_mv Textual: Revistas
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container_title Revista Médica Universitaria
journal_title_str Revista Médica Universitaria
journal_id_str r-1221
container_issue Revista Médica Universitaria
container_volume Vol. 14, no. 1
journal_issue_str Vol. 14, no. 1
tipo_str textuales
type_str_mv Articulos
title_full Reacciones adversas a fármacos
title_fullStr Reacciones adversas a fármacos
Reacciones adversas a fármacos
title_full_unstemmed Reacciones adversas a fármacos
Reacciones adversas a fármacos
description Introduction: Adverse Drugs Reactions (ADR) can seriously affect health and are a frequent medical consultation cause. Sometimes can even go unnoticed if you do not take account of them. To evaluate knowledge and value that the medical team gives to the issue is fundamental in avoid morbidity and mortality of the ADR. Objectives: To determine the level of knowledge of ADR in the medical team. Reflect on the practice about the ADR. Material and methods: Descriptive cross-sectional study through a selfadministered, anonymous and validated survey with closed true / false answer questions on ADR of amiodarone, acenocoumarol, enalapril, furosemide, salbutamol, clonazepam and acetylsalicylic acid. The survey had 51 options for the drugs mentioned. It was consulted about pharmacological training, reading and thinking in ADR prior to prescription, as well as, experiences on the subject. Staff doctors (SD), resident doctors (RD) and 6th year medicine students (S) were included. Statistical analysis: measures of central tendency, scatter measures and Fisher\'s exact test. It was considered significant p <0.05. Outcomes: 107 people were surveyed; 85% were medical doctors (60.4% RD, 39.6% SD) and 15% S. 58.9% were women; average age: 31.3 years. 96% studied pharmacology as a curricular activity during their training. In the previous 6 months, 81.3% had read pharmacology and 16% had done some course about it. At prescribing, 54% thought ALWAYS about ADR, 6.54% report that NEVER read ADR before prescribing and 27.1% made it ALWAYS. 32% answered that they have NEVER had patients with serious ADR; 43% 1 to 3 TIMES and 25% MORE THAN 3 TIMES. About ADR in frequently used drugs, SD and RD answered correctly in 74% each one. Students answered correctly at 64%. About drugs, surveyed people responded correctly at enalapril n 60 (56.07%), acetylsalicylic acid n 57 (53.21%), prednisone n 54 (50.46), amiodarone n 21 (19.62%), salbutamol n 13 (12.14%), piperacillin tazobactam n 12 (11.21%), clonazepam n 12 (11.21%), furosemide n 3 (2.8%), and acenocoumarol n 1 (0.93%). From the comparative analysis between SD and RD, the ALWAYS response in ADR was more frequent in the first ones with SL (p = 0.08). We did not find differences in training or reading on ADR before prescribing between both groups. Conclusion: 54% ALWAYS thought about ADR at prescribing and only 27 referred to read ALWAYS this topic before an indication. The drug that showed less knowledge about was acenocoumarol and the one that showed best knowledge about was enalapril. The level of pharmacological instruction, even in elementary drugs, in public or private medical care system, is low. That is why is more pharmacovigilance is to be implemented in order to prevent ADR, as well as to make the health team aware of the importance of this problem.
dependencia_str_mv Facultad de Ciencias Médicas
title Reacciones adversas a fármacos
spellingShingle Reacciones adversas a fármacos
Conocimiento de la medicación por el médico
Efectos colaterales y reacciones adversas relacionados con medicamentos
Farmacovigilancia
Anci, Cynthia
Carena, José
García Castellanos, Nicolás
Morea, Gastón
Salomón, Susana
Valli Caparroz, Diego
topic Conocimiento de la medicación por el médico
Efectos colaterales y reacciones adversas relacionados con medicamentos
Farmacovigilancia
topic_facet Conocimiento de la medicación por el médico
Efectos colaterales y reacciones adversas relacionados con medicamentos
Farmacovigilancia
author Anci, Cynthia
Carena, José
García Castellanos, Nicolás
Morea, Gastón
Salomón, Susana
Valli Caparroz, Diego
author_facet Anci, Cynthia
Carena, José
García Castellanos, Nicolás
Morea, Gastón
Salomón, Susana
Valli Caparroz, Diego
title_sort Reacciones adversas a fármacos
title_short Reacciones adversas a fármacos
url https://bdigital.uncu.edu.ar/fichas.php?idobjeto=11039
estado_str 3
building Biblioteca Digital
filtrotop_str Biblioteca Digital
collection Artículo de Revista
institution Sistema Integrado de Documentación
indexed_str 2023-04-25 00:36
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