Reacciones adversas a fármacos
Introduction: Adverse Drugs Reactions (ADR) can seriously affect health and are a frequent medical consultation cause. Sometimes can even go unnoticed if you do not take account of them. To evaluate knowledge and value that the medical team gives to the issue is fundamental in avoid morbidity...
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Publicado en: | Revista Médica Universitaria |
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Acceso en línea: | https://bdigital.uncu.edu.ar/fichas.php?idobjeto=11039 |
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10888 1221 Artículo original HospLagClinMed HospLagClinMed HospLagClinMed HospLagClinMed HospLagClinMed HospLagClinMed spa UNCuyo FCM UNCuyo FCM |
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autor_str_mv |
Anci, Cynthia Carena, José García Castellanos, Nicolás Morea, Gastón Salomón, Susana Valli Caparroz, Diego |
disciplina_str_mv |
Ciencias médicas |
descriptores_str_mv |
Conocimiento de la medicación por el médico Efectos colaterales y reacciones adversas relacionados con medicamentos Farmacovigilancia |
description_str_mv |
Introduction:
Adverse Drugs Reactions (ADR) can seriously
affect health and are a frequent medical
consultation cause. Sometimes can even go
unnoticed if you do not take account of them. To
evaluate knowledge and value that the medical
team gives to the issue is fundamental in avoid
morbidity and mortality of the ADR.
Objectives:
To determine the level of knowledge of ADR in
the medical team. Reflect on the practice about
the ADR.
Material and methods:
Descriptive cross-sectional study through a selfadministered,
anonymous and validated survey
with closed true / false answer questions on ADR
of amiodarone, acenocoumarol, enalapril,
furosemide, salbutamol, clonazepam and
acetylsalicylic acid. The survey had 51 options for
the drugs mentioned. It was consulted about
pharmacological training, reading and thinking in
ADR prior to prescription, as well as, experiences
on the subject.
Staff doctors (SD), resident doctors (RD) and 6th
year medicine students (S) were included.
Statistical analysis: measures of central tendency,
scatter measures and Fisher\'s exact test. It was
considered significant p <0.05.
Outcomes:
107 people were surveyed; 85% were medical
doctors (60.4% RD, 39.6% SD) and 15% S. 58.9%
were women; average age: 31.3 years. 96%
studied pharmacology as a curricular activity
during their training. In the previous 6 months,
81.3% had read pharmacology and 16% had done
some course about it. At prescribing, 54%
thought ALWAYS about ADR, 6.54% report that
NEVER read ADR before prescribing and 27.1%
made it ALWAYS. 32% answered that they have
NEVER had patients with serious ADR; 43% 1 to 3
TIMES and 25% MORE THAN 3 TIMES. About ADR
in frequently used drugs, SD and RD answered
correctly in 74% each one. Students answered
correctly at 64%. About drugs, surveyed people
responded correctly at enalapril n 60 (56.07%),
acetylsalicylic acid n 57 (53.21%), prednisone n 54
(50.46), amiodarone n 21 (19.62%), salbutamol n
13 (12.14%), piperacillin tazobactam n 12
(11.21%), clonazepam n 12 (11.21%), furosemide
n 3 (2.8%), and acenocoumarol n 1 (0.93%). From
the comparative analysis between SD and RD, the
ALWAYS response in ADR was more frequent in
the first ones with SL (p = 0.08). We did not find
differences in training or reading on ADR before
prescribing between both groups.
Conclusion:
54% ALWAYS thought about ADR at prescribing
and only 27 referred to read ALWAYS this topic
before an indication. The drug that showed less
knowledge about was acenocoumarol and the
one that showed best knowledge about was
enalapril. The level of pharmacological
instruction, even in elementary drugs, in public or
private medical care system, is low. That is why is
more pharmacovigilance is to be implemented in
order to prevent ADR, as well as to make the
health team aware of the importance of this
problem. Las reacciones adversas a fármacos (RAF) pueden afectar gravemente la salud y son motivo de consulta frecuente. Incluso pueden pasar desapercibidas si no se las piensa. Evaluar el conocimiento y valor que el equipo de salud otorga al tema, es fundamental para evitar la morbimortalidad de las RAF. Objetivos: Determinar el nivel de conocimiento de las reacciones adversas a fármacos (RAF) en el equipo de salud. Reflexionar sobre la propia práctica en relación a las RAF. Materiales y Métodos: Estudio descriptivo transversal a través de encuesta autoadministrada, anónima y validada, con preguntas cerradas de respuesta verdadero/falso sobre RAF de amiodarona, acenocumarol, enalapril, furosemida, salbutamol, clonazepam y ácido acetil salicílico. La encuesta constó de 51 opciones para las drogas citadas. Se consultó sobre la formación académica en farmacología, lectura y pensamiento en RAF previo a la prescripción así como experiencias sobre el tema. Se incluyeron médicos de planta (MP) médicos residentes (MR) y estudiantes (E) del 6º año de medicina. Análisis estadístico: medidas de tendencia central, medidas de dispersión y test exacto de Fisher. Se consideró significativa p<0.05. Resultados: Se encuestaron a 107 personas; 85% eran médicos (60.4% MR, 39.6% MP) y 15% E. El 58.9% fueron mujeres; edad promedio: 31.3 años. Cursaron farmacología como actividad curricular durante su formación el 96%. En los 6 meses previos, 81.3% refieren lecturas sobre farmacología y 16% realizó algún curso sobre el tema. Al momento de prescribir, 54% refieren que SIEMPRE pensaron en RAF. El 6.54% refiere que NUNCA lee previamente RAF antes de prescribir fármacos y 27.1% lo hacen SIEMPRE. El 32% contestó que NUNCA ha tenido pacientes con RAF graves; 43%, de 1 a 3 VECES y 25% MÁS DE 3 VECES. En relación a RAF habituales en drogas de uso frecuente los MP y MR respondieron correctamente el 74% cada uno. Conclusiones: El 54% refieren que SIEMPRE pensó en RAF al momento de prescribir y sólo el 27% refirió leer SIEMPRE sobre el tema antes de una indicación. El fármaco en que se demostró menos conocimiento fue acenocumarol y el mejor conocido fue el enalapril. El nivel de instrucción farmacológico, aún en drogas elementales en la salud pública/privada, es relativamente bajo por lo que se debiera implementar mayor fármacovigilancia para prevenir las RAF, como así también concientizar al equipo de salud sobre la importancia de esta problemática. |
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Reacciones adversas a fármacos |
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Textual: Revistas |
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11039 |
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Artículo de Revista |
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article |
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Revista Médica Universitaria |
journal_title_str |
Revista Médica Universitaria |
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r-1221 |
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Revista Médica Universitaria |
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Vol. 14, no. 1 |
journal_issue_str |
Vol. 14, no. 1 |
tipo_str |
textuales |
type_str_mv |
Articulos |
title_full |
Reacciones adversas a fármacos |
title_fullStr |
Reacciones adversas a fármacos Reacciones adversas a fármacos |
title_full_unstemmed |
Reacciones adversas a fármacos Reacciones adversas a fármacos |
description |
Introduction:
Adverse Drugs Reactions (ADR) can seriously
affect health and are a frequent medical
consultation cause. Sometimes can even go
unnoticed if you do not take account of them. To
evaluate knowledge and value that the medical
team gives to the issue is fundamental in avoid
morbidity and mortality of the ADR.
Objectives:
To determine the level of knowledge of ADR in
the medical team. Reflect on the practice about
the ADR.
Material and methods:
Descriptive cross-sectional study through a selfadministered,
anonymous and validated survey
with closed true / false answer questions on ADR
of amiodarone, acenocoumarol, enalapril,
furosemide, salbutamol, clonazepam and
acetylsalicylic acid. The survey had 51 options for
the drugs mentioned. It was consulted about
pharmacological training, reading and thinking in
ADR prior to prescription, as well as, experiences
on the subject.
Staff doctors (SD), resident doctors (RD) and 6th
year medicine students (S) were included.
Statistical analysis: measures of central tendency,
scatter measures and Fisher\'s exact test. It was
considered significant p <0.05.
Outcomes:
107 people were surveyed; 85% were medical
doctors (60.4% RD, 39.6% SD) and 15% S. 58.9%
were women; average age: 31.3 years. 96%
studied pharmacology as a curricular activity
during their training. In the previous 6 months,
81.3% had read pharmacology and 16% had done
some course about it. At prescribing, 54%
thought ALWAYS about ADR, 6.54% report that
NEVER read ADR before prescribing and 27.1%
made it ALWAYS. 32% answered that they have
NEVER had patients with serious ADR; 43% 1 to 3
TIMES and 25% MORE THAN 3 TIMES. About ADR
in frequently used drugs, SD and RD answered
correctly in 74% each one. Students answered
correctly at 64%. About drugs, surveyed people
responded correctly at enalapril n 60 (56.07%),
acetylsalicylic acid n 57 (53.21%), prednisone n 54
(50.46), amiodarone n 21 (19.62%), salbutamol n
13 (12.14%), piperacillin tazobactam n 12
(11.21%), clonazepam n 12 (11.21%), furosemide
n 3 (2.8%), and acenocoumarol n 1 (0.93%). From
the comparative analysis between SD and RD, the
ALWAYS response in ADR was more frequent in
the first ones with SL (p = 0.08). We did not find
differences in training or reading on ADR before
prescribing between both groups.
Conclusion:
54% ALWAYS thought about ADR at prescribing
and only 27 referred to read ALWAYS this topic
before an indication. The drug that showed less
knowledge about was acenocoumarol and the
one that showed best knowledge about was
enalapril. The level of pharmacological
instruction, even in elementary drugs, in public or
private medical care system, is low. That is why is
more pharmacovigilance is to be implemented in
order to prevent ADR, as well as to make the
health team aware of the importance of this
problem. |
dependencia_str_mv |
Facultad de Ciencias Médicas |
title |
Reacciones adversas a fármacos |
spellingShingle |
Reacciones adversas a fármacos Conocimiento de la medicación por el médico Efectos colaterales y reacciones adversas relacionados con medicamentos Farmacovigilancia Anci, Cynthia Carena, José García Castellanos, Nicolás Morea, Gastón Salomón, Susana Valli Caparroz, Diego |
topic |
Conocimiento de la medicación por el médico Efectos colaterales y reacciones adversas relacionados con medicamentos Farmacovigilancia |
topic_facet |
Conocimiento de la medicación por el médico Efectos colaterales y reacciones adversas relacionados con medicamentos Farmacovigilancia |
author |
Anci, Cynthia Carena, José García Castellanos, Nicolás Morea, Gastón Salomón, Susana Valli Caparroz, Diego |
author_facet |
Anci, Cynthia Carena, José García Castellanos, Nicolás Morea, Gastón Salomón, Susana Valli Caparroz, Diego |
title_sort |
Reacciones adversas a fármacos |
title_short |
Reacciones adversas a fármacos |
url |
https://bdigital.uncu.edu.ar/fichas.php?idobjeto=11039 |
estado_str |
3 |
building |
Biblioteca Digital |
filtrotop_str |
Biblioteca Digital |
collection |
Artículo de Revista |
institution |
Sistema Integrado de Documentación |
indexed_str |
2023-04-25 00:36 |
_version_ |
1764120193874788352 |