The comes and goes of lipid membranes under the lens of computer simulations

When phospholipids dissolve in water they self-assemble into a variety of structures of which bilayers have the greatest biological relevance. Bio-membranes are the most complex examples of lipid bilayers as they have evolved to accommodate the needs of specialized cells, organelles, and other su...

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Autor principal: Del Pópolo, M.
Publicado: 2019
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Acceso en línea:https://bdigital.uncu.edu.ar/fichas.php?idobjeto=12587
date_str_mv 2019-08-14
disciplina_str_mv Bioquímica y Biofísica
Ciencias médicas
todos_str_mv CONICET
autor_str_mv Del Pópolo, M.
dependencia_str_mv Facultad de Ciencias Médicas
descriptores_str_mv Membrana Celular
Metabolismo de los lípidos
object_type_str_mv Ponencia
titulo_str_mv The comes and goes of lipid membranes under the lens of computer simulations
description_str_mv When phospholipids dissolve in water they self-assemble into a variety of structures of which bilayers have the greatest biological relevance. Bio-membranes are the most complex examples of lipid bilayers as they have evolved to accommodate the needs of specialized cells, organelles, and other sub-cellular structures. However, even the simplest lipid bilayer offers a repertoire of behaviours that is amenable of exploration with different levels of resolution in space and time. For example, while certain properties of the membranes are well described considering the membrane as an elastic sheet, others demand a more detailed description that takes into account the atomic nature of the lipids and the forces that keep the bilayer together. Between these two extreme representations of the membrane, one fairly schematic the other very elaborate, there is a range of “coarse-grain” models that can be interrogated with the aid of computer simulations.
id 12587
plantilla_str Producción Científico Académica
record_format Producción Científico Académica
tipo_str textuales
type_str_mv Articulos
title_full The comes and goes of lipid membranes under the lens of computer simulations
title_fullStr The comes and goes of lipid membranes under the lens of computer simulations
The comes and goes of lipid membranes under the lens of computer simulations
title_full_unstemmed The comes and goes of lipid membranes under the lens of computer simulations
The comes and goes of lipid membranes under the lens of computer simulations
description When phospholipids dissolve in water they self-assemble into a variety of structures of which bilayers have the greatest biological relevance. Bio-membranes are the most complex examples of lipid bilayers as they have evolved to accommodate the needs of specialized cells, organelles, and other sub-cellular structures. However, even the simplest lipid bilayer offers a repertoire of behaviours that is amenable of exploration with different levels of resolution in space and time. For example, while certain properties of the membranes are well described considering the membrane as an elastic sheet, others demand a more detailed description that takes into account the atomic nature of the lipids and the forces that keep the bilayer together. Between these two extreme representations of the membrane, one fairly schematic the other very elaborate, there is a range of “coarse-grain” models that can be interrogated with the aid of computer simulations.
title The comes and goes of lipid membranes under the lens of computer simulations
spellingShingle The comes and goes of lipid membranes under the lens of computer simulations
Membrana Celular
Metabolismo de los lípidos
Del Pópolo, M.
topic Membrana Celular
Metabolismo de los lípidos
topic_facet Membrana Celular
Metabolismo de los lípidos
publishDate 2019
author Del Pópolo, M.
author_facet Del Pópolo, M.
title_sort The comes and goes of lipid membranes under the lens of computer simulations
title_short The comes and goes of lipid membranes under the lens of computer simulations
url https://bdigital.uncu.edu.ar/fichas.php?idobjeto=12587
estado_str 3
building Biblioteca Digital
filtrotop_str Biblioteca Digital
collection Producción Científico Académica
institution Sistema Integrado de Documentación
indexed_str 2023-04-25 00:35
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