Bacteriemias por Pseudomonas Aeruginosa
Objectives: To assess the clinical features and morbimortality of Pseudomonas aeruginosa bacteremia compared to Klebsiella spp bacteremia occurred in hospitalized adult patients of an Internal Medicine service.- Material and methods: Protocolized, descriptive and observational study performed in...
Guardado en:
| Publicado en: | Revista Médica Universitaria |
|---|---|
| Autores principales: | , , , , , |
| Materias: | |
| Acceso en línea: | https://bdigital.uncu.edu.ar/fichas.php?idobjeto=3841 |
| Sumario: | Objectives: To assess the clinical features and morbimortality of Pseudomonas
aeruginosa bacteremia compared to Klebsiella spp bacteremia occurred in hospitalized
adult patients of an Internal Medicine service.-
Material and methods: Protocolized, descriptive and observational study performed in a 20
years period. Inclusion criteria: 2 o more positive blood cultures. Data was analized with
Epi Info 6.04 and the criteria of statistically significance was p<0.05.
Results: 282 gram negative bacili bacteremia were found in the study period. 19 were
caused by P.aeruginosa (6.7%) and 76 by Klebsiella (26.9%). No significant differences
were found on average age [53.9 years(DS±17.9 ) vs 58.7 years (DS±15.2)], sex (female
26.3 vs 38.2%) and complications (77.8 vs 77.3%). Neutropenia (52.6 vs
9.2%)(p<0.0001), major comorbidity (94.7 vs 68.4%)(p<0.05), neoplasms (47.4 vs
22.4%)(p<0.05), use of corticosteroids (21.1 vs 3.9%)(p<0.05), immunosupressive drugs
(31.6 vs 7.9%)(p<0.01), thrombocytopenia (77.7 vs 49.3%) (p<0.05) and leukopenia (52.6
vs 21.3%)(p<0.01) were found in a higher frequency among P.aerugionsa bacteremia.
Hypoalbuminemia was more common in Klebsiella spp group (88.5 vs 37.5%)(p<0.001).
No significant differences were found between source of infection (78.9 vs 77.6%), anemia
(84.2 vs 71.2%), infectious complications (84.2 vs 73.7%), descompensation of comorbid
condition (55.6 vs 51.3%) and encephalopathy (36.8 vs 57.9%)(pNS). Mortality within 7
days of admision was significantly higher in P.aeruginosa bacteremia (57.1 vs 12%)
(p<0.01), without differences in crude mortality (36.8 vs 32.9%) (pNS).
Conclusions: P.aeruginosa bacteremia compared to Klebsiella spp. bacteremia were
significantly associated to a higher frequency of neoplasms, leukopenia, thrombocytopenia
and neutropenia, major comorbidity, use of corticosteroids and immunosupressive drug
and mortality within 7 days.
|
|---|
