Películas antibacterianas de poli(3-hidroxibutirato) (PHB)

In this work, films of poly(3-hydroxybutyrate) (PHB) with Irganox 1010 (0.3%, w/pPHB) as antioxidant, glycerol tributyrate (20%, w/pPHB) as plasticizer, and copper (II) sulfate pentahydrate (1 - 7.5%, w/pPHB) as antimicrobial were obtained by melt mixing and thermocompression. The incorporation of t...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Quispe, Mayte Milenka, Villanueva, María Emilia, Copello, Guillermo Javier, López, Olivia Valeria, Villar , Marcelo Armando
Formato:	Online
Lenguaje:	spa
Publicado:	Facultad de Ciencias Aplicadas a la Industria 2023
Acceso en línea:	https://revistas.uncu.edu.ar/ojs3/index.php/revicap/article/view/7038

id	I11-R108article-7038
record_format	ojs
spelling	I11-R108article-70382023-07-31T14:07:09Z Poly(3-hydroxybutyrate) (PHB) films with antibacterial properties Películas antibacterianas de poli(3-hidroxibutirato) (PHB) Quispe, Mayte Milenka Villanueva, María Emilia Copello, Guillermo Javier López, Olivia Valeria Villar , Marcelo Armando In this work, films of poly(3-hydroxybutyrate) (PHB) with Irganox 1010 (0.3%, w/pPHB) as antioxidant, glycerol tributyrate (20%, w/pPHB) as plasticizer, and copper (II) sulfate pentahydrate (1 - 7.5%, w/pPHB) as antimicrobial were obtained by melt mixing and thermocompression. The incorporation of the antimicrobial increased the roughness of films surface. The materials containing Cu (II) sulfate presented lower ductility and mechanical resistance due to the crystals micrometric size. The incorporation of 0.5 % of the antimicrobial increased the WVP due to the high degree of hydration of the salt; however, higher concentrations (2.5 - 7.5 %) reduced this property due to an increased tortuosity. Although the materials presented antibacterial capacity against Staphylococcus aureus (Gram +) and Pseudomonas aeruginosa (Gram -), differences attributed to cell wall of the bacteria were observed. Thus, it was revealed that it is possible to obtain antibacterial PHB films, from the incorporation of a copper salt, that could be used for food, cosmetic or pharmaceutical packaging as well as for biomedical devices. En este trabajo se obtuvieron películas por mezclado en fundido y termocompresión a partir de poli(3-hidroxibutirato) (PHB) con Irganox 1010 (0,3 %, p/pPHB) como antioxidante, tributirato de glicerol (20 %, p/pPHB) como plastificante y sulfato de cobre (II) pentahidratado (0,5 - 7,5 %, p/pPHB) como antimicrobiano. La incorporación del antimicrobiano incrementó la rugosidad de la superficie de las películas. Los materiales que contenían sulfato de Cu (II) presentaron menor ductilidad y resistencia mecánica debido al tamaño micrométrico de los cristales. La incorporación de 0,5 % del antimicrobiano permitió incrementar la WVP debido al elevado grado de hidratación de la sal; sin embargo, concentraciones mayores (2,5 - 7,5 %) redujeron esta propiedad por el incremento de la tortuosidad. Si bien los materiales presentaron capacidad antibacteriana frente a Staphylococcus aureus (Gram +) y Pseudomonas aeruginosa (Gram -), se apreciaron diferencias atribuidas a la pared celular de estas bacterias. Así, se demostró que es posible obtener películas antibacterianas de PHB a partir de la incorporación de una sal de cobre que podrían utilizarse para envases de alimentos, cosméticos o farmacéuticos como así también para dispositivos biomédicos. Facultad de Ciencias Aplicadas a la Industria 2023-07-31 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://revistas.uncu.edu.ar/ojs3/index.php/revicap/article/view/7038 Revista de Ingeniería y Ciencias Aplicadas; Vol. 1 No. 2 (2023): Revista de Ingeniería y Ciencias Aplicadas (RevICAp) Revista de Ingeniería y Ciencias Aplicadas; Vol. 1 Núm. 2 (2023): Revista de Ingeniería y Ciencias Aplicadas (RevICAp) 2796-9444 spa https://revistas.uncu.edu.ar/ojs3/index.php/revicap/article/view/7038/5750 Derechos de autor 2023 Mayte Milenka Quispe, María Emilia Villanueva, Guillermo Javier Copello, Olivia Valeria López, Marcelo Armando Villar http://creativecommons.org/licenses/by-nc-nd/4.0
institution	Universidad Nacional de Cuyo
building	Revistas en línea
filtrotop_str	Revistas en línea
collection	Revista de Ingeniería y Ciencias Aplicadas
journal_title_str	Revista de Ingeniería y Ciencias Aplicadas
institution_str	I-11
repository_str	R-108
language	spa
format	Online
author	Quispe, Mayte Milenka Villanueva, María Emilia Copello, Guillermo Javier López, Olivia Valeria Villar , Marcelo Armando
spellingShingle	Quispe, Mayte Milenka Villanueva, María Emilia Copello, Guillermo Javier López, Olivia Valeria Villar , Marcelo Armando Películas antibacterianas de poli(3-hidroxibutirato) (PHB)
author_facet	Quispe, Mayte Milenka Villanueva, María Emilia Copello, Guillermo Javier López, Olivia Valeria Villar , Marcelo Armando
author_sort	Quispe, Mayte Milenka
title	Películas antibacterianas de poli(3-hidroxibutirato) (PHB)
title_short	Películas antibacterianas de poli(3-hidroxibutirato) (PHB)
title_full	Películas antibacterianas de poli(3-hidroxibutirato) (PHB)
title_fullStr	Películas antibacterianas de poli(3-hidroxibutirato) (PHB)
title_full_unstemmed	Películas antibacterianas de poli(3-hidroxibutirato) (PHB)
title_sort	poly(3-hydroxybutyrate) (phb) films with antibacterial properties
description	In this work, films of poly(3-hydroxybutyrate) (PHB) with Irganox 1010 (0.3%, w/pPHB) as antioxidant, glycerol tributyrate (20%, w/pPHB) as plasticizer, and copper (II) sulfate pentahydrate (1 - 7.5%, w/pPHB) as antimicrobial were obtained by melt mixing and thermocompression. The incorporation of the antimicrobial increased the roughness of films surface. The materials containing Cu (II) sulfate presented lower ductility and mechanical resistance due to the crystals micrometric size. The incorporation of 0.5 % of the antimicrobial increased the WVP due to the high degree of hydration of the salt; however, higher concentrations (2.5 - 7.5 %) reduced this property due to an increased tortuosity. Although the materials presented antibacterial capacity against Staphylococcus aureus (Gram +) and Pseudomonas aeruginosa (Gram -), differences attributed to cell wall of the bacteria were observed. Thus, it was revealed that it is possible to obtain antibacterial PHB films, from the incorporation of a copper salt, that could be used for food, cosmetic or pharmaceutical packaging as well as for biomedical devices.
publisher	Facultad de Ciencias Aplicadas a la Industria
publishDate	2023
url	https://revistas.uncu.edu.ar/ojs3/index.php/revicap/article/view/7038
work_keys_str_mv	AT quispemaytemilenka poly3hydroxybutyratephbfilmswithantibacterialproperties AT villanuevamariaemilia poly3hydroxybutyratephbfilmswithantibacterialproperties AT copelloguillermojavier poly3hydroxybutyratephbfilmswithantibacterialproperties AT lopezoliviavaleria poly3hydroxybutyratephbfilmswithantibacterialproperties AT villarmarceloarmando poly3hydroxybutyratephbfilmswithantibacterialproperties AT quispemaytemilenka peliculasantibacterianasdepoli3hidroxibutiratophb AT villanuevamariaemilia peliculasantibacterianasdepoli3hidroxibutiratophb AT copelloguillermojavier peliculasantibacterianasdepoli3hidroxibutiratophb AT lopezoliviavaleria peliculasantibacterianasdepoli3hidroxibutiratophb AT villarmarceloarmando peliculasantibacterianasdepoli3hidroxibutiratophb
_version_	1800221041692246016

Películas antibacterianas de poli(3-hidroxibutirato) (PHB)

Ejemplares similares